Ap Bio Molecular Genetics Essay

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With respect to the m RNA, the three sites are oriented 5’ to 3’ E-P-A, because ribosomes move toward the 3' end of m RNA.

The A-site binds the incoming t RNA with the complementary codon on the m RNA.

In co-translational translocation, the entire ribosome/m RNA complex binds to the outer membrane of the rough endoplasmic reticulum (ER) and the new protein is synthesized and released into the ER; the newly created polypeptide can be stored inside the ER for future vesicle transport and secretion outside the cell, or immediately secreted.

Many types of transcribed RNA, such as transfer RNA, ribosomal RNA, and small nuclear RNA, do not undergo translation into proteins.

The anticodon is an RNA triplet complementary to the m RNA triplet that codes for their cargo amino acid.

Aminoacyl t RNA synthetases (enzymes) catalyze the bonding between specific t RNAs and the amino acids that their anticodon sequences call for.The P-site holds the t RNA with the growing polypeptide chain.The E-site holds the t RNA without its amino acid, and the t RNA is then released.Translation proceeds in three phases: The three phases of translation initiation polymerase binds to the DNA strand and moves along until the small ribosomal subunit binds to the DNA.Elongation is initiated when the large subunit attaches and termination ends the process of elongation.where the medium and small subunits of the ribosome bind to the t RNA.In eukaryotes, translation occurs in the cytosol or across the membrane of the endoplasmic reticulum in a process called co-translational translocation.t RNAs are small noncoding RNA chains (75-90 nucleotides) that transport amino acids to the ribosome.t RNAs have a site for amino acid attachment, and a site called an anticodon.The successive amino acids added to the chain are matched to successive nucleotide triplets in the m RNA.In this way, the sequence of nucleotides in the template m RNA chain determines the sequence of amino acids in the generated polypeptide.


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